HEPATOPROTECTIVE PROPERTIES OF GLUTARGIN IN LEAD INTOXICATIONS
(experimental studies)

O.L. Apikhtina, A.V. Kotsyuruba, Yu.P. Korkach, E.G. Lampeka

The article describes the experimental studies on the toxic action of lead on the liver. The preparation GLUTARGIN was proposed as a protective substance. Its application on rats, exposed to lead, promoted the decrease of lead content, the level of ROS generation and normalization of of nitric oxide indices metabolism and the content of thiols in the liver, pointing to high hepatoprotective properties of glutargin.

Keywords: lead, hepatotoxic effect, reactive oxygen species, GLUTARGIN, nitric oxide, protective.

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